*This file is part of a program based on the
Bio 4835 Biostatistics class taught at Kean
University in *

Probability theory developed from the study of games of chance like dice and cards. A process like flipping a coin, rolling a die or drawing a card from a deck are called probability experiments. An outcome is a specific result of a single trial of a probability experiment.

Probability theory is the foundation for statistical inference. A probability distribution is a device for indicating the values that a random variable may have. There are two categories of random variables. These are discrete random variables and continuous random variables.

The probability distribution of a discrete random variable specifies all possible values of a discrete random variable along with their respective probabilities.

Examples can be

- Frequency distribution
- Probability distribution (relative frequency distribution)
- Cumulative frequency

Examples of discrete
probability distributions are the binomial distribution and the Poisson
distribution.

**Binomial distribution**

A binomial experiment is a probability experiment with the following
properties.

1. Each trial can have only two outcomes which can be considered success
or failure.

2. There must be a fixed number of trials.

3. The outcomes of each trial must be independent of each other.

4. The probability of success must remain the same in each trial.

The outcomes of a binomial experiment are called a binomial distribution.

**Poisson distribution
**

The Poisson distribution is based on the Poisson process.

1. The occurrences of the events are independent in an interval.

2. An infinite number of occurrences of the event are possible in the interval.

3. The probability of a single event in the interval is proportional to the length of the interval.

4. In an infinitely small portion of the interval, the probability of more than one occurrence of the event is negligible.

A continuous variable can assume any value within a specified interval of values assumed by the variable. In a general case, with a large number of class intervals, the frequency polygon begins to resemble a smooth curve.

A continuous probability distribution is a

The normal distribution is the most important distribution in biostatistics. It is frequently called the Gaussian distribution. The two parameters of the normal distribution are the mean (m) and the standard deviation (s). The graph has a familiar bell-shaped curve.

Graph of a normal distribution

Characteristics of the normal distribution

1. It is symmetrical about m.

2. The mean, median and mode are all equal.

3. The total area under the curve above the x-axis is 1 square unit. Therefore 50% is to the right of m and 50% is to the left of m.

4. Perpendiculars of:

± s contain about 68%;

±2 s contain about 95%;

±3 s contain about 99.7%

of the area under the curve.

A normal distribution is determined by m and s. This creates a family of distributions depending on whatever the values of m and s are. The standard normal distribution has m =0 and s =1.

Finding normal curve areas

1. The table gives areas between - and the value of .

2. Find the z value in tenths in the column at left margin and locate its row. Find the hundredths place in the appropriate column.

3. Read the value of the area (P) from the body of the table where the row and column intersect. Note that P is the probability that a given value of z is as large as it is in its location. Values of P are in the form of a decimal point and four places. This constitutes a decimal percent.

Finding probabilities

We find probabilities using the table and a four-step procedure as illustrated below.

a) What is the probability that z < -1.96?

(1) Sketch a normal curve

(2) Draw a line for z = -1.96

(3) Find the area in the table

(4) The answer is the area to the left of the line P(z < -1.96) = .0250

b) What is the probability that -1.96 < z < 1.96?

(1) Sketch a normal curve

(2) Draw lines for lower z = -1.96, and upper z = 1.96

(3) Find the area in the table corresponding to each value

(4) The answer is the area between the values--subtract lower from upper P(-1.96 < z < 1.96) = .9750 - .0250 = .9500

c) What is the probability that z > 1.96?

(1) Sketch a normal curve

(2) Draw a line for z = 1.96

(3) Find the area in the table

(4) The answer is the area to the right of the line; found by subtracting table value from 1.0000; P(z > 1.96) =1.0000 - .9750 = .0250

The normal distribution is used as a model to study many different variables. We can use the normal distribution to answer probability questions about random variables. Some examples of variables that are normally distributed are human height and intelligence.

In this explanation we add an additional step. Following the model of the normal distribution, a given value of x must be converted to a z score before it can be looked up in the z table.

(1) Write the given information

(2) Sketch a normal curve

(3) Convert x to a z score

(4) Find the appropriate value(s) in the table

(5) Complete the answer

Illustrative Example: Total fingerprint ridge count in humans is approximately normally distributed with mean of 140 and standard deviation of 50. Find the probability that an individual picked at random will have a ridge count less than 100. We follow the steps to find the solution.

(1) Write the given information

m = 140

s = 50

x = 100

(3) Convert x to a z score

(4) Find the appropriate value(s) in the table

A value of z = -0.8 gives an area of .2119 which corresponds to the probability P (z < -0.8)

(5) Complete the
answer

The probability that x is less than 100 is .2119.