Edward Hyde Jr. , Ph.D.
Publications
Ballatore, C., Brunden, K.R., Piscitelli, F., James, M.J., Crowe, A., Yao, Y., Hyde, E.G., Trojanowski, J.Q., Lee, V.Y.-M., Smith, A.B. (2010). Discovery of Brain-Penetrant, Orally Bioavailable Aminothienopyridazine Inhibitors of Tau Aggregation. Journal of Medicinal Chemistry. 53(9):3739-3747.
Luk, K.C., Hyde, E.G., Trojanowski, J.Q. and Lee, V. M.-Y. (2007). A sensitive florescence polarization technique for rapid screening of alpha-synuclein oligomerization/ fibrilization inhibitors. Biochemistry. 46 (44): 12522 -12529.
Crowe, A., Ballatore, C., Hyde, E., Trojanowski, J.Q., and Lee, V.M.-Y. (2007). High throughput screening for small molecule inhibitors of heparin-induced tau fibril formation. Biochemical & Biophysical Research Communications. 358(1):1-6.
Ballatore, C., Hyde E., Deiches RF., Lee, VM. V.M.-Y, Trojanowski, J.Q., Huryn, D., and Smith, A.B. 3rd. (2007). Paclitaxel C-10 carbamates: potential candidates for the treatment of neurodegenerative tauopathies. Bioorganic & Medicinal Chemistry Letters. 17(13):3642-6.
Han, H., Stessin, A., Roberts, J., Hess, K., Gautam, N., Kamenetsky, M., Lou, O., Hyde, E., Nathan, N., Muller, W.A., Buck, J., Levin, L.R. and Nathan C. (2005). Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils. Journal of Experimental Medicine. 202(3):353-61.